Articles scientifiques
Early-life exposure to mixtures of endocrine-disrupting chemicals and a multi-domain health score in preschool children
ENVIRON RES. 2025 MAY
Amine I, Guillien A, Bayat S, Lyon-Caen S, Ouidir M, Sabaredzovic A, Sakhi AK, Thomsen C, Valmary-Degano S, Philippat C, Siroux V.
Prenatal exposure to synthetic phenols assessed in multiple urine samples and dysregulation of steroid hormone homeostasis in two European cohorts.
ENVIRON HEALTH PERSPECT. 2025 MARCH
Jedynak P, Bustamante M, Rolland M, Mustieles V, Thomsen C, Sakhi AK, Sabaredzovic A, Foraster M, Gascon M, Gómez-Roig MD, Llurba E, Rivas I, Ouellet-Morin I, Bayat S, Lyon-Caen S, Pozo OJ, Vrijheid M, Sunyer J, Slama R, Dadvand P, Philippat C.
PFAS exposure during pregnancy: Implications for placental health and functioning
ENVIRON INT. 2025 MARCH
Khan S, Ouidir M, Lemaitre N, Jovanovic N, Bayat S, Lyon-Caen S, Hoffmann P, Desseux M, Thomsen C, Couturier-Tarrade A, Småstuen Haug L, Valmary-Degano S, Siroux V, Slama R, Alfaidy N, Philippat C.
Early-life exposures to phenols, parabens and phthalates and fat mass at 3 years of age in the SEPAGES cohort
ENVIRON RES. 2025 FEBRUARY
Colombini M, Heude B, Lyon-Caen S, Thomsen C, Sakhi AK, Valmary-Degano S, Bayat S, Slama R, Philippat C, Ouidir M.
Intrafamilial associations of sleep multitrajectory groups between ages of 3 and 60 months in the SEPAGES cohort
SLEEP HEALTH. 2024 DECEMBER
Kim M, Lyon-Caen S, Bayat S, Philippat C, Plancoulaine S.
Associations between pre- and post-natal exposure to phthalate and DINCH metabolites and gut microbiota in one-year old children
ENVIRON POLLUT. 2024 DECEMBER
Davias A, Lyon-Caen S, Rolland M, Iszatt N, Thomsen C, Sabaredzovic A, Sakhi AK, Monot C, Rayah Y, Ilhan ZE, Philippat C, Eggesbø M, Lepage P, Slama R.
Perinatal Exposure to Phenols and Poly- and Perfluoroalkyl Substances and Gut Microbiota in One-Year-Old Children
Environ Sci Technol. 2024 SEPTEMBER
Davias A, Lyon-Caen S, Rolland M, Iszatt N, Thomsen C, Haug LS, Sakhi AK, Monot C, Rayah Y, Ilhan ZE, Jovanovic N, Philippat C, Eggesbo M, Lepage P, Slama R.
Epigenetic footprints: Investigating placental DNA methylation in the context of prenatal exposure to phenols and phthalates
ENVIRON INT. 2024 JULY
Jedynak P, Siroux V, Broséus L, Tost J, Busato F, Gabet S, Thomsen C, Sakhi AK, Sabaredzovic A, Lyon-Caen S, Bayat S, Slama R, Philippat C, Lepeule J.
Placental DNA methylation signatures of prenatal air pollution exposure and potential effects on birth outcomes: an analysis of three prospective cohorts
LANCET PLANET HEALTH. 2024 MAY
Broséus L, Guilbert A, Hough I, Kloog I, Chauvaud A, Seyve E, Vaiman D, Heude B, Chevrier C, Tost J, Slama R, Lepeule J.
Fetal and Infancy Exposure to Phenols, Parabens, and Phthalates and Anthropometric Measurements up to 36 Months, in the Longitudinal SEPAGES Cohort
ENVIRON HEALTH PERSPECT. 2024 MAY
Ouidir M, Cissé AH, Botton J, Lyon-Caen S, Thomsen C, Sakhi AK, Sabaredzovic A, Bayat S, Slama R, Heude B, Philippat C.
Associations between synthetic phenols, phthalates, and placental growth/function: a longitudinal cohort with exposure assessment in early pregnancy
HUM REPROD OPEN. 2024 APRIL
Jovanovic N, Mustieles V, Althuser M, Lyon-Caen S, Alfaidy N, Thomsen C, Sakhi AK, Sabaredzovic A, Bayat S, Couturier-Tarrade A, Slama R, Philippat C.
Parents' Sleep Multi-Trajectory Modelling from 3 to 36 Months Postpartum in the SEPAGES Cohort
NAT SCI SLEEP. 2024 MARCH
Kim M, Lyon-Caen S, Bayat S, Philippat C, Plancoulaine S
Effects of personal exposure to the oxidative potential of PM2.5 on oxidative stress biomarkers in pregnant women
TOTAL ENVIRON. 2024 FEBRUARY
Marsal A, Sauvain JJ, Thomas A, Lyon-Caen S, Borlaza LJS, Philippat C, Jaffrezo JL, Boudier A, Darfeuil S, Elazzouzi R, Lepeule J, Chartier R, Bayat S, Slama R, Siroux V, Uzu G
Intra-breath changes in respiratory mechanics are sensitive to history of respiratory illness in preschool children: the SEPAGES cohort
S.Respir Res, 2024 FEBRUARY
Siroux V, Boudier A, Lyon-Caen S, Quentin J, Gioria Y, Hantos Z, Slama R, Pin I, Bayat
Longitudinal Associations between Prenatal Exposure to Phthalates and Steroid Hormones in Maternal Hair Samples from the SEPAGES Cohort
ENVIRONMENTAL SOCIETY AND TECHNOLOGY, 2023 DECEMBER
Mustieles V, Lascouts A, Pozo OJ, Haro N, Lyon-Caen S, Jedynak P, Bayat S, Thomsen C, Sakhi AK, Sabaredzovic A, Slama R, Ouellet-Morin I, Philippat C
Prenatal exposure to triclosan assessed in multiple urine samples and placental DNA methylation
ENVIRON POLLUT. 2023 OCTOBER
Jedynak P, Broséus L, Tost J, Busato F, Gabet S, Thomsen C, Sakhi AK, Pin I, Slama R, Lepeule J, Philippat C
Prenatal exposure to synthetic phenols and phthalates and child respiratory health from 2 to 36 months of life
ENVIRON POLLUT. 2023 AUGUST
Coiffier O, Lyon-Caen S, Boudier A, Quentin J, Gioria Y, Pin I, Bayat S, Thomsen C, Sakhi AK, Sabaredzovic A, Slama R, Philippat C, Siroux V
Early-Life Exposure to a Mixture of Phenols and Phthalates in Relation to Child Social Behavior: Applying an Evidence-Based Prioritization to a Cohort with Improved Exposure Assessment
Environ Health Perspect, 2023 AUGUST
Mustieles V, Rolland M, Pin I, Thomsen C, Sakhi AK, Sabaredzovic A, Muckle G, Guichardet K, Slama R, Philippat C
Personal exposure to PM2.5 oxidative potential and its association to birth outcomes
J EXPO SCI ENVIRON EPIDEMIOL. 2023 MAY
Borlaza LJS, Uzu G, Ouidir M, Lyon-Caen S, Marsal A, Weber S, Siroux V, Lepeule J, Boudier A, Jaffrezo JL, Slama R
Maternal imprinting and determinants of neonates’ immune function in the SEPAGES mother-child cohort
FRONTIERS IN IMMUNOLOGY, 2023 APRIL
Olivier Manches, Khémary Um, Anne Boudier, Yasmina Maddouri, Sarah Lyon-Caen, Sam Bayat, Rémy Slama, Claire Philippat, Valérie Siroux, Laurence Chaperot
Pre-natal exposure to NO2 and PM2.5 and newborn lung function: An approach based on repeated personal exposure measurements
ENVIRONMENTAL RESEARCH, 2023 MARCH
Johanna Lepeule, Isabelle Pin, Anne Boudier, Joane Quentin, Sarah Lyon-Caen, Karine Supernant , Emie Seyve , Ryan Chartier, Remy Slama, Valérie Siroux
Association of Prenatal and Postnatal Exposures to Warm or Cold Air Temperatures With Lung Function in Young Infants
JAMA NATWORK OPEN, 2023 MARCH
Ariane Guilbert, Ian Hough, Emie Seyve, Matthieu Rolland, Joane Quentin, Rémy Slama, Sarah Lyon-Caen, Itai Kloog, Sam Bayat, Valérie Siroux, Johanna Lepeule
Effects of early exposure to phthalates on cognitive development and visual behavior at 24 months
ENVIRON RES. 2023 FEBRUARY
Rolland M, Lyon-Caen S, Thomsen C, Sakhi AK, Sabaredzovic A, Bayat S, Slama R, Méary D, Philippat C.
Exposure to a mixture of non-persistent environmental chemicals and neonatal thyroid function in a cohort with improved exposure assessment
ENVIRONMENT INTERNATIONAL, 2023 FEBRUARY
Ophélie Coiffier, Dorothy Nakiwala, Matthieu Rolland, Andres Malatesta, Sarah Lyon-Caen, Benoît Chovelon, Patrice Faure, Anne Sophie Gauchez, Dorra Guergour, Amrit K. Sakhi, Azemira Sabaredzovic, Cathrine Thomsen, Isabelle Pin, Rémy Slama, Christelle Corne, Claire Philippat
Prenatal Exposure to PM2:5 Oxidative Potential and Lung Function in Infants and Preschool- Age Children: A Prospective Study
ENVIRONMENTAL HEALTH PERSPECTIVES, 2023 JANUARY
Anouk Marsal,Rémy Slama, Sarah Lyon-Caen, Lucille Joanna S. Borlaza, Jean-Luc Jaffrezo, Anne Boudier, Sophie Darfeuil, Rhabira Elazzouzi, Yoann Gioria , Johanna Lepeule, Ryan Chartier, Isabelle Pin, Joane Quentin, Sam Bayat, Gaëlle Uzu, Valérie Siroux
Effects of early exposure to phthalates on cognitive development and visual behavior at 24 months
ENVIRONMENTAL RESEARCH, 2022 DECEMBER
Matthieu Rolland, Sarah Lyon-Caen, Cathrine Thomsen, Amrit K. Sakhi, Azemira Sabaredzovic , Sam Bayat, Rémy Slama, David Méary , Claire Philippat
Phenol and Phthalate Effects on Thyroid Hormone Levels during Pregnancy: Relying on In Vitro Assays and Adverse Outcome Pathways to Inform an Epidemiological Analysis
ENVIRONMENTAL HEALTH PERSPECTIVES, 2022 NOVEMBER
Dorothy Nakiwala, Pamela D. Noyes, Patrice Faure, Benoît Chovelon, Christelle Corne, Anne Sophie Gauchez, Dorra Guergour, Sarah Lyon-Caen, Amrit K. Sakhi, Azemira Sabaredzovic, Cathrine Thomsen, Isabelle Pin, Rémy Slama, Claire Philippat
Personal exposure to PM2.5 oxidative potential and its association to birth outcomes
JOURNAL OF EXPOSURE SCIENCE & ENVIRONMENTAL EPIDEMIOLOGY, 2022 OCTOBER
Lucille Joanna S. Borlaza , Gaëlle Uzu, Marion Ouidir, Sarah Lyon-Caen, Anouk Marsal, Samuël Weber, Valérie Siroux, Johanna Lepeule, Anne Boudier, Jean-Luc Jaffrezo, Rémy Slama
Early delivery following chronic and acute ambient temperature exposure: a comprehensive survival approach
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2022 SEPTEMBER
Ian Hough, Matthieu Rolland , Ariane Guilbert, Emie Seyve, Barbara Heude, Rémy Slama, Sarah Lyon-Caen, Isabelle Pin, Cécile Chevrier, Itai Kloog , Johanna Lepeule
Pregnancy Exposure to Phenols and Anthropometric Measures in Gestation and at Birth
EPIDEMIOLOGY, 2022 SEPTEMBER
Paulina Jedynak, Matthieu Rolland,Isabelle Pin,Cathrine Thomsen, Amrit K. Sakhi, Azemira Sabaredzovic, Claire Philippat, and Rémy Slama
Association between household cleaning product profiles evaluated by the Ménag'Score ® index and asthma symptoms among women from the SEPAGES cohort
INT ARCH OCCUP AND ENVIRON HEALTH, 2022 APRIL
Pierre Lemire, Emmanuel Chevallier, Sarah Lyon-Caen, Etienne Sévin, Anne Boudier, Emilie Pacheco Da Silva, Christian De Thuin, Rémy Slama, Orianne Dumas, Valérie Siroux, Nicole Le Moual, SEPAGES Study Group
Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview
ENVIRON EPIDEMIOL, 2021 OCTOBER
Martine Vrijheid, Xavier Basagaña, Juan R Gonzalez, Vincent W V Jaddoe, Genon Jensen, Hector C Keun, Rosemary R C McEachan, Joana Porcel, Valerie Siroux, Morris A Swertz, Cathrine Thomsen, Gunn Marit Aasvang, Sandra Andrušaitytė, Karine Angeli, Demetris Avraam, Ferran Ballester, Paul Burton, Mariona Bustamante, Maribel Casas, Leda Chatzi, Cécile Chevrier, Natacha Cingotti, David Conti, Amélie Crépet, Payam Dadvand, Liesbeth Duijts, Esther van Enckevort, Ana Esplugues, Serena Fossati, Ronan Garlantezec, María Dolores Gómez Roig, Regina Grazuleviciene, Kristine B Gützkow, Mònica Guxens, Sido Haakma, Ellen V S Hessel, Lesley Hoyles, Eleanor Hyde, Jana Klanova, Jacob D van Klaveren, Andreas Kortenkamp, Laurent Le Brusquet, Ivonne Leenen, Aitana Lertxundi, Nerea Lertxundi, Christos Lionis, Sabrina Llop, Maria-Jose Lopez-Espinosa, Sarah Lyon-Caen, Lea Maitre, Dan Mason, Sandrine Mathy, Edurne Mazarico, Tim Nawrot, Mark Nieuwenhuijsen, Rodney Ortiz, Marie Pedersen, Josep Perelló, Míriam Pérez-Cruz, Claire Philippat, Pavel Piler, Costanza Pizzi , Joane Quentin, Lorenzo Richiardi, Adrian Rodriguez , Theano Roumeliotaki , José Manuel Sabin Capote , Leonardo Santiago, Susana Santos, Alexandros P Siskos, Katrine Strandberg-Larsen, Nikos Stratakis, Jordi Sunyer, Arthur Tenenhaus, Marina Vafeiadi, Rebecca C Wilson, John Wright, Tiffany Yang, Remy Slama
Pre- and early post-natal exposure to phthalates and DINCH in a new type of mother-child cohort relying on within-subject pools of repeated urine samples
ENVIRON POLLUT, 2021 OCTOBER
Claire Philippat, Matthieu Rolland, Sarah Lyon-Caen, Isabelle Pin, Amrit K Sakhi, Azemira Sabaredzovic, Cathrine Thomsen, Rémy Slama
Associations between a mixture of phenols and phthalates and child behaviour in a French mother–child cohort with repeated assessment of exposure
ENV INT, 2021 JUNE
Ariane Guilbert, Matthieu Rolland, Isabelle Pin, Cathrine Thomsen, Amrit K. Sakhi, Azemira Sabaredzovic, Rémy Slama, Karine Guichardet, Claire Philippat, Sepages Study Group
Comparison of a Barcode-Based Smartphone Application to a Questionnaire to Assess the Use of Cleaning Products at Home and Their Association with Asthma Symptoms
INT J ENVIRON RES PUBLIC HEALTH, 2021 MARCH
Pierre Lemire, Sofia Temam, Sarah Lyon-Caen, Catherine Quinot, Etienne Sévin, Sophie Remacle, Karine Supernant, Rémy Slama, Orianne Dumas, Valérie Siroux, Nicole Le Moual, The Sepages Study Group
Exposure to Phenols During Pregnancy and the First Year of Life in a New Type of Couple-Child Cohort Relying on Repeated Urine Biospecimens
Environ Int, 2020 June
Matthieu Rolland, Sarah Lyon-Caen, Amrit K Sakhi, Isabelle Pin, Azemira Sabaredzovic, Cathrine Thomsen, Rémy Slama, Claire Philippat, SEPAGES study group
Use of Personal Care Products During Pregnancy in Relation to Urinary Concentrations of Select Phenols: A Longitudinal Analysis From the SEPAGES Feasibility Study
Int J Hyg Environ Health, 2020 June
Dorothy Nakiwala, Céline Vernet, Sarah Lyon-Caen, Anna Lavorel, Matthieu Rolland, Claire Cracowski, Isabelle Pin, Antonia M Calafat, Rémy Slama, Claire Philippat, SEPAGES study group
Deciphering the Impact of Early-Life Exposures to Highly Variable Environmental Factors on Foetal and Child Health: Design of SEPAGES Couple-Child Cohort
Int J Environ Res Public Health, 2019 October
Sarah Lyon-Caen, Valérie Siroux, Johanna Lepeule, Philippe Lorimier, Pierre Hainaut, Pascal Mossuz, Joane Quentin, Karine Supernant, David Meary, Laurence Chaperot, Sam Bayat, Flemming Cassee, Sarah Valentino, Anne Couturier-Tarrade, Delphine Rousseau-Ralliard, Pascale Chavatte-Palmer 0, Claire Philippat, Isabelle Pin, Rémy Slama, The Sepages Study Group
An Empirical Validation of the Within-subject Biospecimens Pooling Approach to Minimize Exposure Misclassification in Biomarker-based Studies
Epidemiology, 2019 September
Céline Vernet, Claire Philippat, Lydiane Agier, Antonia M Calafat, Xiaoyun Ye, Sarah Lyon-Caen, Pierre Hainaut, Valérie Siroux, Enrique F Schisterman, Rémy Slama
Personal assessment of the external exposome during pregnancy and childhood in Europe
Environ Res. 2019 July
David Donaire-Gonzalez, Ariadna Curto, Antònia Valentín, Sandra Andrusaityte, Xavier Basagaña, Maribel Casas, Leda Chatzi, Jeroen de Bont, Montserrat de Castro, Audrius Dedele, Berit Granum, Regina Grazuleviciene, Mariza Kampouri, Sarah Lyon-Caen, Cyntia B Manzano-Salgado, Gunn Marit Aasvang, Rosemary McEachan, Carin Helena Meinhard-Kjellstad, Eirini Michalaki, Pau Pañella, Inga Petraviciene, Per E Schwarze, Rémy Slama, Oliver Robinson, Ibon Tamayo-Uria, Marina Vafeiadi, Dagmar Waiblinger, John Wright, Martine Vrijheid, Mark J Nieuwenhuijsen
Exposure to Phthalate Metabolites, Phenols and Organophosphate Pesticide Metabolites and Blood Pressure During Pregnancy
Int J Hyg Environ Health, 2019 April
Charline Warembourg, Xavier Basagaña, Chiara Seminati, Jeroen de Bont, Berit Granum, Sarah Lyon-Caen, Cyntia B Manzano-Salgado, Isabelle Pin, Amrit K Sakhi, Valérie Siroux, Rémy Slama, Jose Urquiza, Martine Vrijheid, Cathrine Thomsen, Maribel Casas
Variability of Urinary Concentrations of Non-Persistent Chemicals in Pregnant Women and School-Aged Children
Environ Int, 2018 December
Maribel Casas, Xavier Basagaña, Amrit K Sakhi, Line S Haug, Claire Philippat, Berit Granum, Cyntia B Manzano-Salgado, Céline Brochot, Florence Zeman, Jeroen de Bont, Sandra Andrusaityte, Leda Chatzi, David Donaire-Gonzalez, Lise Giorgis-Allemand, Juan R Gonzalez, Esther Gracia-Lavedan, Regina Grazuleviciene, Mariza Kampouri, Sarah Lyon-Caen, Pau Pañella, Inga Petraviciene, Oliver Robinson, Jose Urquiza, Marina Vafeiadi, Céline Vernet, Dagmar Waiblinger, John Wright, Cathrine Thomsen, Rémy Slama, Martine Vrijheid
Human Early Life Exposome (HELIX) Study: A European Population-Based Exposome Cohort
BMJ Open, 2018 September
Léa Maitre, Jeroen de Bont, Maribel Casas, Oliver Robinson , Gunn Marit Aasvang, Lydiane Agier, Sandra Andrušaitytė, Ferran Ballester, Xavier Basagaña, Eva Borràs, Céline Brochot, Mariona Bustamante , Angel Carracedo, Montserrat de Castro, Audrius Dedele, David Donaire-Gonzalez, Xavier Estivill, Jorunn Evandt, Serena Fossati, Lise Giorgis-Allemand, Juan R Gonzalez, Berit Granum, Regina Grazuleviciene, Kristine Bjerve Gützkow, Line Småstuen Haug, Carles Hernandez-Ferrer, Barbara Heude, Jesus Ibarluzea , Jordi Julvez , Marianna Karachaliou 0, Hector C Keun, Norun Hjertager Krog, Chung-Ho E Lau, Vasiliki Leventakou, Sarah Lyon-Caen, Cyntia Manzano, Dan Mason, Rosemary McEachan, Helle Margrete Meltzer, Inga Petraviciene, Joane Quentin, Theano Roumeliotaki, Eduard Sabido, Pierre-Jean Saulnier, Alexandros P Siskos, Valérie Siroux, Jordi Sunyer , Ibon Tamayo, Jose Urquiza, Marina Vafeiadi, Diana van Gent, Marta Vives-Usano, Dagmar Waiblinger, Charline Warembourg, Leda Chatzi, Muireann Coen, Peter van den Hazel, Mark J Nieuwenhuijsen, Rémy Slama, Cathrine Thomsen, John Wright, Martine Vrijheid
Within-Day, Between-Day, and Between-Week Variability of Urinary Concentrations of Phenol Biomarkers in Pregnant Women
Env Health Perpect, 2018 March
Céline Vernet, Claire Philippat, Antonia M Calafat, Xiaoyun Ye, Sarah Lyon-Caen, Valérie Siroux, Enrique F Schisterman, Rémy Slama
Estimation of Exposure to Atmospheric Pollutants During Pregnancy Integrating Space-Time Activity and Indoor Air Levels: Does It Make a Difference?
Environ Int, 2015 November
Marion Ouidir, Lise Giorgis-Allemand, Sarah Lyon-Caen, Xavier Morelli, Claire Cracowski, Sabrina Pontet, Isabelle Pin, Johanna Lepeule, Valérie Siroux, Rémy Slama