Institut National de la Santé et de la Recherche Médicale (INSERM) U1209
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The SEPAGES team has developed numerous partnerships to collect, analyze, and enhance the data of this large research collaboration.
By opening their doors to the SEPAGES team, they facilitated the recruitment of pregnant women starting at the first trimester of pregnancy.
Thanks to the involvement of the medical teams of the Grenoble-area maternity wards region that participated in the SEPAGES study, samples were acquired at the time of delivery and just after birth during the postpartum period. The participating maternity wards are those of the Clinique Mutualiste, the Clinique Belledonne, the Clinique des Cèdres, and l’Hôpital Couple Enfant.
The University Hospital Center is the promoter of the SEPAGES cohort. The Biological Resource Center of the Grenoble Alpes University Hospital Center, which is a certified biobank, oversees aliquoting and storage of all biological samples of the cohort. Over time, the Biological Resource Center has aliquoted 80 000 samples! The Institute of Biology and Pathology of the Grenoble Alpes University Hospital is responsible for assessing thyroid hormones, selenium, and urinary iodine.
provides the cohort’s scientific team with air pollution data that, in addition to data from personal dosimeters, can be used to estimate volunteers’ exposure to different pollutants (PM2.5, PM10, NO2, ozone).
Babylab specializes in the study of the development of sensory abilities and motor skills of infants or very young children. Within the framework of the SEPAGES study, eye-tracking measurements were made on two-year-old children.
of the Institute for the Advancement of Biosciences collaborates with the SEPAGES team and is responsible for assessing immunological markers in the blood drawn during pregnancy and in cord blood.
of the Institute of Environmental Geoscience collaborates with the SEPAGES team and is responsible for analyzing the oxidative potential of PM2.5 filters from MicroPem microsensors.
of the Micalis Institute at INRAE is responsible for analyzing the microbiota from the meconium and stool samples collected from the cohort.
is a large health research center in Barcelona, Spain. For many years, the scientific team of the SEPAGES cohort has collaborated with the environmental epidemiology teams at this international research center. Within the framework of the SEPAGES cohort, some 50 SEPAGES women also participated in the protocol of the European HELIX project coordinated by ISGLOBAL.
is funded by the General Investment Commissioner. All data from the SEPAGES cohort are securely stored on this platform.
developed the SEPAGES cohort data-collection tool.
developed MicroPem (the tool used in the cohort to measure personal exposure to PM2.5). RTI provides technical assistance to the SEPAGES cohort team.
is in charge of chemical assessments of biological samples.
is in charge of epigenotyping biological samples.
is in charge of assessing steroid hormones in biological samples.
We also work with other birth cohorts in Europe through European collaborations and projects: EDEN, ELFE, PELAGIE, INMA, BISC, BIB, MoBA, Generation R…